Tobey Maguire Spider-Man / Peter Parker Willem Dafoe Green Goblin / Norman Osborn Kirsten Dunst Mary Jane Watson James Franco Harry Osborn Cliff Robertson Ben Parker Rosemary Harris May Parker J.K. Simmons J. Jonah Jameson Joe Manganiello Flash Thompson Gerry Becker Maximilian Fargas Bill Nunn Joseph 'Robbie' Robertson Jack Betts Henry Balkan Stanley Anderson General Slocum Ron Perkins Dr. Mendel Stromm Michael Papajohn Carjacker K.K. Dodds Simkins Ted Raimi Hoffman Bruce Campbell Ring Announcer Elizabeth Banks Miss Brant John Paxton Houseman Peter Appel Cabbie Stan Lee Man in Fair (uncredited)